Nucleic acid in vivo - in vivo-jetPEI™
Non-viral gene delivery to animals is easy with in vivo-jetPEI™ transfection reagent. Simply mix your DNA (or siRNA) with this reagent and administer to animals for gene expression in multiple tissues.
With in vivo-jetPEI™, you can also deliver genes by different modes into different species based on your needs (even humans in GMP conditions). You'll avoid experimental and regulatory hassles by choosing in vivo-jetPEI™ in place of virus for gene delivery.
This reagent can be made under GMP conditions and customized to target specific cells.
Figure : Non-invasive bioluminescence of a living mouse following systemic delivery of in vivo-jetPEI™/DNA complexes.
Features:
- Successful delivery of DNA, siRNA and oligonucleotides in vivo
- Multiple modes of administration in many species
- RNAi with in vivo-jetPEI™
- No detectable inflammatory response
- Currently used in several phase I-II clinical trials
- Reproducible results
Specifications:
| CATALOG # | Amount of reagent | Amount of glucose solution |
|---|---|---|
| 201-10G | 0.1ml | 10 mL |
| 201-50G | 0.5 mL | 2 x 10 mL |
0.1ml of in vivo-jetPEI™ is sufficient to perform up to 20 intravenous injections in mouse with 50 µg of DNA.
For more information on in vivo-jetPEI™, click here.
